use up的問題，透過圖書和論文來找解法和答案更準確安心。 我們找到下列問答集和資訊懶人包

American Manhood: A Concise History of Masculinity in U.s. History and Culture

為了解決use up的問題，作者Carroll, Bret 這樣論述：

While the concepts of manhood and masculinity have assumed an established place in gender and historical studies and masculinity is the subject of wide popular interest and discussion, there is currently no up-to-date, comprehensive historical overview of the subject. American Manhood will introd

uce readers to the dynamic interplay between the perceptions and experiences we call "masculinity" and major social, cultural, political, and economic developments in our history. Its central argument will be that Americans of different racial, class, ethnic, and regional groups have historically us

ed concepts of masculine identity to gender relations of power and national belonging in ways that attempt either to entrench or to stake their claims to positions of authority and legitimacy in American life. Gender, the book assumes and will demonstrate, provides a crucial analytic category for un

derstanding U.S. history. The book will cover the period from roughly the early seventeenth century to the present. It will utilize a combination of chronological and topical approaches to present a state-of-the-art narrative, reflective of current historical scholarship, to a broad general audience

. The anticipated audience will bring to their reading a familiarity with recent popular discussions of masculinity; American Manhood will use accessible prose to reveal to them the enormous complexity, diversity, and historical rootedness of the topic - to deepen readers' understanding of a subject

they thought they knew.

use up進入發燒排行的影片

區塊鏈技術在台灣二手車市場應用之實證研究

為了解決use up的問題，作者蘇祐 這樣論述：

近年來的二手車市場交易量皆比新車市場高的多，且每年逐漸上升，此市場日益壯大，價格機制卻還是相當混亂，相當不透明，故此本研究以改善台灣二手車市場資訊不對稱問題為發想，設計一套網頁系統，以以太坊區塊鏈為系統底層，且成立一個二手車聯盟來管理該系統，有意願加入此系統的車主需將車輛移至與聯盟配合之檢修場，在確認資料無誤後，聯盟會將該車輛的資料上傳至區塊鏈系統上，以供系統參與者查閱。 本研究透過設計區塊鏈系統進行實作實驗，依據區塊鏈的不可篡改性來用以改善台灣二手車市場資訊不對稱問題，並使用Node.js SDK工具提供網頁客戶端，模擬車輛資料上傳的流程，最後提出三項實驗數據以檢驗新的系統架構設計適確性

，以及檢驗資料的正確性。實驗結果顯示，本研究所提出之二手車區塊鏈系統確實可改善二手車市場資訊不對稱的問題，藉由區塊鏈的不可篡改性，讓資料上傳後就無法修改，就算覆蓋過去鏈上也都能查到相對的紀錄，確保鏈上資料的正確性，讓其餘參與者在系統上查閱時，能夠信任這份資料，進一步改善過去消費者只能以車主所提供之資料作為參考，讓二手車市場資訊更加透明，進一步提高消費者對市場的滿意度及忠誠度。

Oto-Endoscopy in Small Animal Medicine and Surgery

為了解決use up的問題，作者Kureshi, Munir,Bhutta, Mahmood F. 這樣論述：

Ear diseases are one of the most common problems in veterinary medicine, but are often misdiagnosed and mismanaged due to inadequate visualization of the ear. Oto-Endoscopy in Small Animal Medicine and Surgery is written as a practical manual, and outlines the endoscopic approach to diagnosing an

d managing ear disease in small animal practice. It will be of value both to those with limited or no experience of endoscopy of the ear, as well as more experienced practitioners. It discusses set up of the endoscope for ear disease, practical considerations for use, and showcases a range of ear co

nditions diagnosed and managed endoscopically. It also shows use of the endoscope as an adjunct to surgery, either via the ear canal or through the bulla. Each topic and condition is demonstrated using high resolution images, and links to online videos. Edited by Dr Kureshi, a veterinarian with over

two decades of experience in ear endoscopy, and Prof Bhutta, a world renown expert in human ear surgery, makes this a first of its kind, an indispensable reference for basic and advanced practitioners in the field. There is no previous book on ear endoscopy in veterinary medicine, but this is defin

itely an emerging and establishing field. The two lead editors ran the first endoscopic ear surgery course for small animals in the USA in 2021, which was well attended and had excellent feedback. Editors were asked to run the same course in the US in 2022, and are considering running the course in

the UK and Brazil in the near future. They believe endoscope is the gold standard for diagnosis of ear disease, and those utilising such tools in their practice is set to grow. Oto-Endoscopy in Small Animal Medicine and Surgery appeals to dermatologists, internal medicine specialists, surgeons, radi

ologists, and neurologists, and several specialty groups.

An Integrated Approach For Uncovering Novel DNA Methylation Biomarkers For Non-small Cell Lung Carcinoma

為了解決use up的問題，作者VAIBHAV KUMAR SUNKARIA 這樣論述：

Introduction - Lung cancer is one of primal and ubiquitous cause of cancer related fatalities in the world. Leading cause of these fatalities is non-small cell lung cancer (NSCLC) with a proportion of 85%. The major subtypes of NSCLC are Lung Adenocarcinoma (LUAD) and Lung Small Cell Carcinoma (LUS

C). Early-stage surgical detection and removal of tumor offers a favorable prognosis and better survival rates. However, a major portion of 75% subjects have stage III/IV at the time of diagnosis and despite advanced major developments in oncology survival rates remain poor. Carcinogens produce wide

spread DNA methylation changes within cells. These changes are characterized by globally hyper or hypo methylated regions around CpG islands, many of these changes occur early in tumorigenesis and are highly prevalent across a tumor type.Structure - This research work took advantage of publicly avai

lable methylation profiling resources and relevant comorbidities for lung cancer patients extracted from meta-analysis of scientific review and journal available at PubMed and CNKI search which were combined systematically to explore effective DNA methylation markers for NSCLC. We also tried to iden

tify common CpG loci between Caucasian, Black and Asian racial groups for identifying ubiquitous candidate genes thoroughly. Statistical analysis and GO ontology were also conducted to explore associated novel biomarkers. These novel findings could facilitate design of accurate diagnostic panel for

practical clinical relevance.Methodology - DNA methylation profiles were extracted from TCGA for 418 LUAD and 370 LUSC tissue samples from patients compared with 32 and 42 non-malignant ones respectively. Standard pipeline was conducted to discover significant differentially methylated sites as prim

ary biomarkers. Secondary biomarkers were extracted by incorporating genes associated with comorbidities from meta-analysis of research articles. Concordant candidates were utilized for NSCLC relevant biomarker candidates. Gene ontology annotations were used to calculate gene-pair distance matrix fo

r all candidate biomarkers. Clustering algorithms were utilized to categorize candidate genes into different functional groups using the gene distance matrix. There were 35 CpG loci identified by comparing TCGA training cohort with GEO testing cohort from these functional groups, and 4 gene-based pa

nel was devised after finding highly discriminatory diagnostic panel through combinatorial validation of each functional cluster.Results – To evaluate the gene panel for NSCLC, the methylation levels of SCT(Secritin), FOXD3(Forkhead Box D3), TRIM58(Tripartite Motif Containing 58) and TAC1(Tachikinin

1) were tested. Individually each gene showed significant methylation difference between LUAD and LUSC training cohort. Combined 4-gene panel AUC, sensitivity/specificity were evaluated with 0.9596, 90.43%/100% in LUAD; 0.949, 86.95%/98.21% in LUSC TCGA training cohort; 0.94, 85.92%/97.37 in GEO 66

836; 0.91,89.17%/100% in GEO 83842 smokers; 0.948, 91.67%/100% in GEO83842 non-smokers independent testing cohort. Our study validates SCT, FOXD3, TRIM58 and TAC1 based gene panel has great potential in early recognition of NSCLC undetermined lung nodules. The findings can yield universally accurate

and robust markers facilitating early diagnosis and rapid severity examination.