ih的問題，透過圖書和論文來找解法和答案更準確安心。 我們找到下列問答集和資訊懶人包

Lha Yudit’’ih (We Always Find a Way): Bringing the Tŝilhqot’’in Title Case Home

為了解決ih的問題，作者 這樣論述：

人蔘皂甙 M1 抑制人類口腔癌之效果及作用機轉

為了解決ih的問題，作者理昱傑 這樣論述：

口腔鱗狀上皮細胞癌(Oral squamous cell carcinoma, OSCC)占臺灣所有惡性腫瘤的 5.8%，發病率逐漸上升，為全世界常見的惡性腫瘤，患者存活率極低，因此需要新的有效治療方法來控制口腔鱗狀上皮細胞癌。本篇研究我們製備人蔘皂甙 M1 (20-O--D-glucopyranosyl-20(S)-protopanaxadiol)，為人蔘皂甙主要的去醣基化代謝物，經由真菌 SP-LSL-002 於原料三七葉生物轉化而得，並用於探討人蔘皂甙 M1 於口腔癌細胞及動物模式之抗癌作用及其作用機制。研究結果顯示，人蔘皂甙 M1 可抑制人類口腔癌鱗狀上皮細胞株 SAS 和 OEC

-M1 之存活率。進一步探討人蔘皂甙 M1 之作用機轉，我們發現人蔘皂甙 M1 可增加口腔鱗狀上皮癌細胞之 Bak、Bad 和 p53 蛋白表現，並造成細胞 DNA 斷裂、細胞週期停滯於 G1 期、PI/Annexin V 雙重染色呈現陽性以及 Caspase-3/9 活化，進而促進細胞凋亡。研究結果也證明，人蔘皂甙 M1 可顯著降低 SAS 和 OEC-M1 細胞株之細胞群落生成和遷移能力，並降低癌細胞轉移相關蛋白 Vimentin 之表現。除此之外，以口服或皮下注射給予人蔘皂甙 M1 可明顯抑制 SAS 腫瘤細胞異種移植小鼠之腫瘤生長。綜合以上結果，人蔘皂甙 M1 具有潛力成為口腔癌之治療

藥物。

Advanced Numerical Modelling of Wave Structure Interaction

為了解決ih的問題，作者 這樣論述：

Dr. David M. Kelly received a first-class Bachelors Degree in Environmental Physics with Mathematics from the University of East Anglia Norwich (UK) in 2000. Dr. Kelly later obtained a PhD. in Civil Engineering from the University of Nottingham (UK), with Prof. Nicholas Dodd as his thesis advisor, i

n January 2009. Dr. Kelly’s PhD thesis focused on developing numerical models for swash zone hydro- morphodynamics. Following this Dr. Kelly worked as a research associate on a knowledge transfer partnership (KTP) between the University of Nottingham and HR Wallingford funded by the UK government. D

r. Kelly was then employed by HR Wallingford as a research engineer and later a senior research engineer. During his time at HR Wallingford Dr. Kelly was responsible for the development and maintenance of a number of commercial CFD codes. In particular Dr. Kelly developed a commercial tsunami propag

ation model and worked on innovative solutions for two-way full Navier Stokes based solvers for fluid structure interactions. Along with Dr. A. Dimakopoulos at HR Wallingford Dr. Kelly co-developed a two phase Navier Stokes solver to simulate oscillating water column wave energy devices for commerci

al application. Dr. Kelly and colleagues at HR Wallingford and the University of Bath have pioneered the use of hybrid Eulerian-Lagrangian particle in cell (PIC) techniques for coastal engineering applications. Dr. Kelly has worked closely with Électricité de France (EDF) R&D to develop several aspe

cts of the TELEMAC modeling suite. Specifically Dr. Kelly has contributed to the numerical modeling of suspended sediment in TELEMAC 2D and recently the advection and diffusion of tracers in TELEMAC 3D. Dr. Kelly’s work forms part of the official TELEMAC modeling suite. Dr Kelly currently works as a

n Assistant Professor at the International Hurricane Research Center at Florida International University where he is the principal developer of the new dynamic adaptive mesh, massively parallel storm surge model. Dr. Kelly has published work in several prestigious international journals including th

e Journal of Fluid Mechanics, Computers and Fluids, International Journal for Numerical Methods in Fluids and the SIAM Journal on Scientific Computing (SISC) and co-supervised two PhD students at UK Universities.Dr. Aggelos Dimakopoulos ([email protected])is a practicing Civil Enginee

r (MEng, MSc, PhD) and an expert in CFD applications to coastal and open channel flows. He has over 13 years of experience in developing and using CFD models. He graduated as a Doctor of Civil Engineering from the University of Patras, Greece and his PhD thesis was on designing and numerically imple

menting a novel turbulent modelling approach for wave breaking in the surf zone. After that he spent one year in Instituto Superior Tecnico as a post-doc researcher and in University of Cyprus as a visiting researcher, where he was mainly involved in CFD modelling of channel flow through vegetation

arrays. Dr. Dimakopoulosjoined HR Wallingford (UK) in May 2012, and since then, he has been involved in a range of commercial and research projects; in particular, he has been involved in developing the CFD capabilities of the company. Dr. Dimakopoulos has been involved in numerous consultancy studi

es concerning the application of CFD models to assess and optimize the design of coastal and hydraulic structures. He is currently leading a team of 2 engineers and 3 PhD students and he is always interested in the development and the application of CFD models, aiming to reduce uncertainties caused

by the interaction of waves, structures and turbulence.Dr. Pablo Higuera Caubilla ([email protected])graduated in 2010, obtaining a first-in-class degree in Civil Engineering. He immediately pursued a MSc in Coastal and Port Engineering (2012) and a PhD in Civil/Coastal Engineering (2015), all of th

em at the University of Cantabria (Spain) and linked to the Environmental Hydraulics Institute IH Cantabria. During his PhD, Dr Higuera studied all sorts of coastal engineering processes using Computational Fluid Dynamics (CFD). As part of his PhD, he developed the open source numerical model ihFoam

, based on OpenFOAM framework. Major achievements included the development of new modules for wave generation and active wave absorption, flow through porous media and a thorough validation of the model. After obtaining his PhD, Dr Higuera was a postdoc at Imperial College London, where he studied f

low and rock mechanics within armour layers in breakwaters, based on CFD and Finite Element Method - Discrete Elements Method (FEMDEM) models, aiding in the incorporation of hydrodynamic forcings to Solidity Project. Dr Higuera is currently a Research Fellow at the National University of Singapore,

where he continues the study of wave-driven hydrodynamics with OpenFOAM. In his free time he continues to contribute to the coastal community with open source developments, now under the name of OlaFoam Project.