glycolic acid功效的問題，透過圖書和論文來找解法和答案更準確安心。 我們找到下列問答集和資訊懶人包

glycolic acid功效進入發燒排行的影片

氧化石墨烯-膠原蛋白複合材料奈米介面應用於肺部纖維化抑制之功效

為了解決glycolic acid功效的問題，作者蔡沛璇 這樣論述：

誌謝 i中文摘要 iiABSTRACT iiiCONTENTS ivLIST OF FIGURES viiiLIST OF TABLES xABBREVIATION xiChapter 1 Introduction 121.1 Foreign body reaction related fibrosis 121.1.1 Introduction of fibrosis 121.1.2 Foreign body reaction 121.1.3 Myofibroblast differentiati

on mechanism 131.1.4 Macrophages M1/M2 phenotype homeostasis 131.2 Anti-fibrosis strategies for implants 141.2.1 Antifibrotic drugs 141.2.2 Design principles for implants 151.2.2.1 Material selection 151.2.2.2 Decellularization 151.2.2.3 Pore size 151.2.2

.4 Surface modification 161.3 Nanopatterned biointerface 161.3.1 Common patterning methods 161.3.1.1 Photolithography 171.3.1.2 Electron beam lithography (EBL) 171.3.1.3 Soft lithography 171.3.1.4 Others 171.3.2 Different types of patterns 181.3.2.1

Nanogrooves 181.3.2.2 Nanocolumns/pillars 181.3.2.3 Nanopits 191.3.3 Nanopatterned biointerface for anti-fibrosis 191.4 Graphene oxide application and advantages 201.4.1 Graphene oxide 201.4.2 Biocompatibility of graphene oxide 201.4.3 Graphene oxide applic

ation for implants 211.4.3.1 2D planar substrate 211.4.3.2 3D Scaffold 211.4.4 Graphene oxide composite advantages in anti-fibrosis 22Chapter 2 Motivation 26Chapter 3 Materials and methods 273.1 Materials 273.1.1 Synthesis of Graphene oxide conjugated collag

en 273.1.2 Human lung fibroblast cell line (HFL-1) 273.1.3 Human monocytic cell line (THP-1) 283.1.4 Differentiation of THP-1 monocytes into macrophages 283.2 Material analysis of Graphene oxide-collagen (GO-COL) 293.2.1 X-ray photoelectron spectroscopy (XPS) 293.2.2

Fourier transform infrared spectroscopy (FTIR) 293.2.3 Scanning electron microscope (SEM) 293.2.4 Atomic force microscope (AFM) 293.3 Cell viability 303.4 Flow cytometry 303.5 Immunofluorescence staining 313.6 Western Blot 323.7 TGF-β1 ELISA assay 323

.8 IL-6/CCL2 ELISA assay 333.9 Statistical analysis 33Chapter 4 Results and discussions 344.1 GO-COL composite characterization 344.1.1 GO-COL composite synthesis 344.1.2 XPS spectrometry analysis 354.1.3 FTIR analysis 354.1.4 Surface morphology 354.1.

5 Surface roughness 364.2 In vitro cytocompatibility analysis 364.3 GO-COL inhibits myofibroblasts differentiation 374.3.1 Morphology of HFL-1 fibroblasts on GO-COL 374.3.2 Immunofluorescence staining of myofibroblast marker (α-SMA) expression 374.4 GO-COL decreases

M2 subtype macrophages polarization 384.4.1 Morphology of THP-1 macrophages on GO-COL 384.4.2 CD163 expression of THP-1 macrophages 394.5 Anti-fibrosis efficiency of fibroblasts and macrophages co-culture 404.5.1 Ratio of fibroblast/macrophage co-culture 404.5.2 Co-cult

ure of fibroblast/macrophage 404.5.3 Fibrosis related proteins α-SMA/Collagen-1 expression 414.5.4 Anti-fibrosis efficiency in longer timepoints 414.5.5 Fibrosis related cytokine TGF-β/proinflammatory cytokine IL-6 secretion 414.6 Application of GO-COL on implantable material

s 424.6.1 GO-COL coating on Ti/Nitinol disks 434.6.2 Cell prroliferation of GO-COL coated Ti/Nitinol disks 434.6.3 Anti-fibrosis efficiency of GO-COL coated Ti/Nitinol disks 434.6.4 Cytokine expression of GO-COL coated Ti/Nitinol disks 44Chapter 5 Conclusions 45REFER

ENCES 65APPENDIX 72